THE LSD CRYSTAL DIARIES

Within the LSD-sure crystal composition, the facet chain of the lid residue L209EL2 sorts in depth hydrophobic contacts with both LSD and bordering residues in TMs III, IV, and V (Determine 4C). If the lid moved apart to show the binding pocket in simulation, several of these contacts broke. We So hypothesized that L209EL2 functions like a latch, c